Publications

Peer-reviewed articles

Din, M.O.*, Danino, T.*, Prindle, A., Skalak, M., Selimkhanov, J., Allen, K., Julio, E., Atolia, E., Tsimring, L.S., Bhatia, S.N. and Hasty, J., 2016. Synchronized cycles of bacterial lysis for in vivo delivery. Nature, 536(7614), pp.81–85. (*co-first authors) (Link)

Scott, S.R., Din, M.O., Bittihn, P., Xiong, L., Tsimring, L.S. and Hasty, J., 2017. A stabilized microbial ecosystem of self-limiting bacteria using synthetic quorum-regulated lysis. Nature Microbiology, 2, 17083. (Link)

Bittihn, P.*, Din, M.O.*, Tsimring, L.S. and Hasty, J., 2018. Rational engineering of synthetic microbial systems: from single cells to consortia. Current Opinion in Microbiology, 45, pp.92–99. (*co-first authors) (Link)

Liao, M.J., Din, M.O., Tsimring, L.S. and Hasty, J., 2019. Rock–paper–scissors: engineered population dynamics increase genetic stability. Science, 365(6457), pp.1045–1049. (Link)

Din, M.O.*, Martin, A.*, Razinkov, I., Csicsery, N. and Hasty, J., 2020. Interfacing gene circuits with microelectronics through engineered population dynamics. Science Advances, 6(21), eaaz8344. (*co-first authors) (Link)

Kobayashi, H., Gieniec, K.A., Wright, J.A., Wang, T., Asai, N., Mizutani, Y., Iida, T., Ando, R., Suzuki, N., Lannagan, T.R.M., Ng, J.Q., Hara, A., Shiraki, Y., Mii, S., Ichinose, M., Vrbanac, L., Lawrence, M.J., Sammour, T., Uehara, K., Davies, G., Lisowski, L., Alexander, I.E., Hayakawa, Y., Butler, L.M., Zannettino, A.C.W., Din, M.O., Hasty, J., Burt, A.D., Leedham, S.J., Rustgi, A.K., Mukherjee, S., Wang, T.C., Enomoto, A., Takahashi, M., Worthley, D.L. and Woods, S.L., 2021. The balance of stromal BMP signaling mediated by GREM1 and ISLR drives colorectal carcinogenesis. Gastroenterology, 160(4), pp.1224–1239. (Link)

Leeflang, J., Wright, J.A., Worthley, D.L., Din, M.O. and Woods, S.L., 2025. Evolutionary adaptation of probiotics in the gut: selection pressures, optimization strategies, and regulatory challenges. npj Biofilms and Microbiomes, 11, 96. (contributed as a senior author) (Link)

Ryu, B., Avalon, N.E., Cuau, M., Almaliti, J., Din, M.O., Brennan, C., Glukhov, E., Knight, R., Gerwick, L. and Gerwick, W.H., 2025. Cyanobacteria join the kahalalide conversation: genome and metabolite evidence for structurally related peptides. Journal of the American Chemical Society, 147(35), pp.31800–31810. (Link)

Minich, J.J., Allsing, N., Din, M.O., Tisza, M.J., Maleta, K., McDonald, D., Hartwick, N., Mamerto, A., Brennan, C., Hansen, L., Shaffer, J., Murray, E., Duong, T., Knight, R., Stephenson, K., Manary, M. and Michael, T.P., 2025. Culture-independent meta-pangenomics enabled by long-read metagenomics reveals associations with pediatric undernutrition. Cell, 188(23), pp.6666–6686.e25. (Link)

Weng, Y., Guccione, C., McDonald, D., Oles, R., Devkota, S., Kopylova, E., Sepich-Poore, G.D., Salido, R.A., Din, M.O., Song, S.J., Curtius, K., Chu, H., Bartko, A., Hasty, J. and Knight, R., 2025. Calculating fast differential genome coverages among metagenomic sources using micov. Communications Biology, 8, 1624. (Link)

Preprints

Din, M.O.*, Salido, R.*, Wright, G., Brennan, C., Ambre, M., Hansen, L., Boyer, T., Cao, J., Oles, R., Patel, L., et al., 2025. Versatile wastewater monitoring of pathogens and antimicrobial resistance enabled by metatranscriptomics and long-read metagenomics. Research Square (preprint). (Link)

Additional manuscripts in preparation on long-read metagenomics to come soon.